The Gremlin 1 Polyclonal Antibody, Biotin Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to GREM1. This antibody recognizes Human, Mouse, and Rat antigen. The Gremlin 1 Polyclonal Antibody, Biotin Conjugated has been validated for the following applications: Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Acts as inhibitor of monocyte chemotaxis (By similarity)